Cagrilintide is an amylin analogue that helps regulate appetite. In a randomized trial of over 3400 patients who were overweight or obese and had 1 weight related complication, individuals assigned to a combination Obesity Week 2025 Medications Combined GLP 1 amylin analog bests monotherapy for HbA1c drop, weight loss in diabetes What are the side effects of Weygovy (cagrilintide)? Safety, tolerability, pharmacokinetics, and pharmacodynamics of concomitant administration of multiple doses of cagrilintide with semaglutide 24 mg for weight management: a randomised, controlled, phase 1b trial ScienceDirect