INTRAMUSCULAR INJECTION SITES Intramuscular (IM) injections are given directly into the muscle, where the medication is absorbed more quickly than subcutaneous injections. There are several Nwokeiwu Valentine How to self inject intramuscular vitamin B12 Overview Guy's and St Thomas' NHS Foundation Trust Intramuscular injection: Locations and administration Methylcobalamin 10,000mcg injectable, 10mL (lyophilized) Defy Medical Safe IM Injection Site Intramuscular injection should always be given in the **upper outer quadrant of the gluteal region** to prevent sciatic nerve injury. Key nursing points: Upper outer quadrant =