New!!! A Novel Therapy Called Dihexa Shows Promise In Alzheimer's Disease Patients Medicine With Heart Dihexa (also known as PNB 0408) is an experimental small molecule derived from angiotensin IV. It was engineered to cross the bloodbrain barrier and has shown synaptogenic effects in preclinical models. The often quoted How does Dihexa Powder work in the brain? Salispharm Dihexa (also known as PNB 0408) is an experimental small molecule derived from angiotensin IV. It was engineered to cross the bloodbrain barrier and has shown synaptogenic effects in preclinical models. The often quoted D I H E X A is having a moment right now and I get why. When something gets labeled as brain repair or synapse growth, it spreads FAST especially in communities