Glutathione in liver diseases and hepatotoxicity. Semantic Scholar Hepatic Glutathione Synthesis: The Liver's Antioxidant Powerhouse Glutathione (GSH) is the most abundant intracellular antioxidantand the liver is its primary production site. Through a tightly regulated, ATP dependent pathway, hepatocytes Metabolic functions of the liver Deranged Physiology JCI Chronic stressinduced ANPEP drives liver cancer progression by increasing glutathione synthesis and inhibiting ferroptosis Dysregulation of glutathione synthesis in liver disease ScienceDirect