Glucose 6 phosphate Dehydrogenase (G6PD) Enzyme ROS Scavenger Biochemistry & Hematology YouTube Although G6PD deficiency, which can cause problems in red blood cells upon certain triggers, is the most common human enzyme defect, affecting over 400 million people, including over 1 in 10 Black Diabetes causes inhibition of glucose 6 phosphate dehydrogenase via activation of PKA, which contributes to oxidative stress in rat kidney cortex American Journal of Physiology Renal Physiology American Physiological Society Frontiers Recent findings in the regulation of G6PD and its role in diseases Frontiers The global role of G6PD in infection and immunity