Weed And Donating Blood: All You Need To Know Moose Labs We all know smoking and vaping isn't great for your health. But it doesn't stop you from being a blood or plasma donor. Just make sure to wait one hour after donating Smoking (or vaping) doesn't affect your ability to donate blood. Help us bust this myth by sharing our post. Smoking (or vaping) doesn't affect your ability to donate blood. Help us bust this myth by sharing our post. Vaping, Venous Valves, and Vein Disease